三豬窟

　　
　　本中心特邀請學有專精之師資研究人選，進行公開演講，誠摯邀請蒞臨指導。詳細時間、地點、主題與講者如下：

時間：民國99年12月17日(星期五) 12：00～13:00

地點：林口長庚兒童醫院3J教室

主題：Next Steps in Identifying Genetic Variants Contributing to Disease Risk: Building upon GWAS

講者：張書瑋博士/中央研究院生物醫學科學研究所 博士後研究員

摘要: In this talk, I first summarize the principles for undertaking genome-wide association analysis and the practical guide and considerations in finding disease-associated genes or variants. Then I focus on the use of haplotype-based approaches to finding epistasis in complex trait studies. Two data mining methods, multifactor dimensionality reduction (MDR) and classification and regression tree (CART), with the concept of haplotypes considering haplotype uncertainties to detect gene-gene interactions have been shown to be valuable for researchers to gain more insight into identifying genetic risk factors for complex diseases.



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